N-Methylleukotriene C4
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- $165 - $1235
- Product name: N-Methylleukotriene C4
- CAS: 131391-65-6
- MF: C31H49N3O9S
- MW: 639.81
- EINECS:
- MDL Number:MFCD11113154
- Synonyms:N-[S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-Carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetren-1-yl]-N-(L-γ-glutamyl)-L-cysteinyl]-N-methylglycine;N-Methylleukotriene C4;NMLTC4;N-METHYL LTC4;FPLBRCJNODNRQZ-UYCXAPQFSA-N;Glycine, N-methyl-L-γ-glutamyl-S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]-L-cysteinyl-;N methyl Leukotriene C4,N-methyl Leukotriene C-4,Nmethyl Leukotriene C4
4 prices
Selected condition：
Brand
- Cayman Chemical
- TRC
Package
- 25μg
- 50μg
- 100μg
- 2.5mg
- ManufacturerCayman Chemical
- Product number13390
- Product descriptionN-methyl Leukotriene C4 ≥97%
- Packaging25μg
- Price$165
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13390
- Product descriptionN-methyl Leukotriene C4 ≥97%
- Packaging50μg
- Price$313
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13390
- Product descriptionN-methyl Leukotriene C4 ≥97%
- Packaging100μg
- Price$592
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberL330388
- Product descriptionN-methylLeukotrieneC4
- Packaging2.5mg
- Price$1235
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Cayman Chemical | 13390 | N-methyl Leukotriene C4 ≥97% | 25μg | $165 | 2024-03-01 | Buy |
| Cayman Chemical | 13390 | N-methyl Leukotriene C4 ≥97% | 50μg | $313 | 2024-03-01 | Buy |
| Cayman Chemical | 13390 | N-methyl Leukotriene C4 ≥97% | 100μg | $592 | 2024-03-01 | Buy |
| TRC | L330388 | N-methylLeukotrieneC4 | 2.5mg | $1235 | 2021-12-16 | Buy |
Properties
Boiling point :965.7±65.0 °C(Predicted)
Density :1.202±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 1 mg/ml; Ethanol:H20 (95:5): 2 mg/ml; PBS (pH 7.2): 100 μg/ml
pka :2.23±0.10(Predicted)
Density :1.202±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 1 mg/ml; Ethanol:H20 (95:5): 2 mg/ml; PBS (pH 7.2): 100 μg/ml
pka :2.23±0.10(Predicted)
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Danger | ||||||||||||||||||||||||||||||
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Description
Produced by neutrophils, macrophages, mast cells, and by transcellular metabolism in platelets, leukotriene C4 (LTC4) is the parent cysteinyl leukotriene formed by the LTC4 synthase-catalyzed conjugation of glutathione to LTA4. It is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) and exhibits potent smooth muscle contracting activity. LTC4, however, is rapidly metabolized to LTD4 and LTE4, which makes the characterization of LTC4 pharmacology difficult. N-methyl Leukotriene C4 (N-methyl LTC4) is a synthetic analog of LTC4 that is not readily metabolized to LTD4 and LTE4.It acts as a potent and selective CysLT2 receptor agonist exhibiting EC50 values of 122 and > 2,000 nM at the human CysLT2 and CysLT1 receptors, respectively. It has essentially the same potency as LTC4 at both the human and murine receptors CysLT2 receptors. N-methyl LTC4 is potent and active in vivo, causing vascular leak in mice overexpressing the human CysLT2 receptor but not in CysLT2 receptor knockout mice.More related product prices
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