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ChemicalBook >> CAS DataBase List >> Notoginsenoside Ft1

Notoginsenoside Ft1

Notoginsenoside Ft1 price.
  • $26 - $1069.3
  • Product name: Notoginsenoside Ft1
  • CAS: 155683-00-4
  • MF: C47H80O17
  • MW: 917.13
  • EINECS:
  • MDL Number:MFCD22125013
  • Synonyms:Notoginsenoside Ft1;(3beta,12beta,20R)-12,20-Dihydroxydammar-24-en-3-yl O-beta-D-xylopyranosyl-(1- 2)-O-beta-D-glucopyranosyl-(1-2)-beta-D-glucopyranoside;product/153944;β-D-Glucopyranoside, (3β,12β,20R)-12,20-dihydroxydammar-24-en-3-yl O-β-D-xylopyranosyl-(1→2)-O-β-D-glucopyranosyl-(1→2)-;(2S,3R,4S,5R)-2-[(2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-17-[(2R)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxan-3-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol
17 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • AvaChem
  • Biorbyt Ltd
  • Cayman Chemical
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
Package
  • 500μg
  • 1mg
  • 5mg
  • 10mg
  • 20mg
  • 25mg
  • 50mg
  • 100mg
  • ManufacturerAK Scientific
  • Product number8189AH
  • Product descriptionNotoginsenosideFT1
  • Packaging5mg
  • Price$413
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number8189AH
  • Product descriptionNotoginsenosideFT1
  • Packaging10mg
  • Price$608
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN2245
  • Product descriptionNotoginsenosideFt1
  • Packaging20mg
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2929
  • Product descriptionNotoginsenoside Ft1
  • Packaging5mg
  • Price$490
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb594406
  • Product descriptionNotoginsenoside Ft1
  • Packaging20mg
  • Price$499.8
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb105495
  • Product descriptionNotoginsenoside Ft1 >98%,Standard References Grade
  • Packaging20mg
  • Price$569.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb594406
  • Product descriptionNotoginsenoside Ft1
  • Packaging100mg
  • Price$1069.3
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number24976
  • Product descriptionNotoginsenoside Ft1 ≥95%
  • Packaging1mg
  • Price$26
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number24976
  • Product descriptionNotoginsenoside Ft1 ≥95%
  • Packaging500μg
  • Price$32
  • Updated2023-01-06
  • Buy
  • ManufacturerCayman Chemical
  • Product number24976
  • Product descriptionNotoginsenoside Ft1 ≥95%
  • Packaging5mg
  • Price$83
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number24976
  • Product descriptionNotoginsenoside Ft1 ≥95%
  • Packaging10mg
  • Price$102
  • Updated2024-03-01
  • Buy
  • ManufacturerCrysdot
  • Product numberCD32002316
  • Product descriptionNotoginsenosideFt1 98+%
  • Packaging10mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD32002316
  • Product descriptionNotoginsenosideFt1 98+%
  • Packaging25mg
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD32002316
  • Product descriptionNotoginsenosideFt1 98+%
  • Packaging50mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD32002316
  • Product descriptionNotoginsenosideFt1 98+%
  • Packaging100mg
  • Price$440
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDCS-084
  • Product descriptionNotoginsenosideFt1 >98%,StandardReferencesGrade
  • Packaging20mg
  • Price$280
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 8189AH NotoginsenosideFT1 5mg $413 2021-12-16 Buy
AK Scientific 8189AH NotoginsenosideFT1 10mg $608 2021-12-16 Buy
ApexBio Technology N2245 NotoginsenosideFt1 20mg $400 2021-12-16 Buy
AvaChem 2929 Notoginsenoside Ft1 5mg $490 2021-12-16 Buy
Biorbyt Ltd orb594406 Notoginsenoside Ft1 20mg $499.8 2021-12-16 Buy
Biorbyt Ltd orb105495 Notoginsenoside Ft1 >98%,Standard References Grade 20mg $569.5 2021-12-16 Buy
Biorbyt Ltd orb594406 Notoginsenoside Ft1 100mg $1069.3 2021-12-16 Buy
Cayman Chemical 24976 Notoginsenoside Ft1 ≥95% 1mg $26 2024-03-01 Buy
Cayman Chemical 24976 Notoginsenoside Ft1 ≥95% 500μg $32 2023-01-06 Buy
Cayman Chemical 24976 Notoginsenoside Ft1 ≥95% 5mg $83 2024-03-01 Buy
Cayman Chemical 24976 Notoginsenoside Ft1 ≥95% 10mg $102 2024-03-01 Buy
Crysdot CD32002316 NotoginsenosideFt1 98+% 10mg $70 2021-12-16 Buy
Crysdot CD32002316 NotoginsenosideFt1 98+% 25mg $140 2021-12-16 Buy
Crysdot CD32002316 NotoginsenosideFt1 98+% 50mg $250 2021-12-16 Buy
Crysdot CD32002316 NotoginsenosideFt1 98+% 100mg $440 2021-12-16 Buy
DC Chemicals DCS-084 NotoginsenosideFt1 >98%,StandardReferencesGrade 20mg $280 2021-12-16 Buy

Properties

Boiling point :997.8±65.0 °C(Predicted)
Density :1.36±0.1 g/cm3(Predicted)
solubility :DMF: 20 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 15 mg/ml; Ethanol: 5 mg/ml
form :A crystalline solid
pka :12.84±0.70(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Notoginsenoside Ft1 is a saponin originally isolated from P. notoginseng with diverse biological activities. It induces proliferation, migration, and tube formation of human umbilical vein endothelial cells (HUVECs) via nuclear translocation of hypoxia-inducible factor-1α (HIF-1α) and activation of the PI3K/AKT and Raf/MEK/ERK signaling pathways in a manner dependent on mammalian target of rapamycin (mTOR). Notoginsenoside Ft1 (45 μM) induces cell cycle arrest at the S and G2/M phases and promotes apoptosis of SH-SY5Y cells. It increases cGMP levels and induces relaxation of isolated precontracted rat mesenteric arteries, effects that are reversed by the nitric oxide synthase inhibitor L-NAME and ODQ , an inhibitor of soluble guanylyl cyclase. In vivo, notoginsenoside Ft1 (0.25, 2.5, and 25 mg/kg) promotes angiogenesis and decreases wound diameter in a mouse model of punched-hole ear injury. Notoginsenoside Ft1 (1.25 mg/kg) decreases tail bleeding time and increases thrombus weight in a rat tail bleeding assay. Topical administration of notoginsenoside Ft1 increases mRNA expression of the collagen expression, fibroblast proliferation, and scar formation genes COL1A1, COL3A1, TGF-β1, TGF-β3, and fibronectin, promotes neovascularization, reduces monocyte infiltration, and shortens wound closure time in a db/db mouse model of diabetic foot ulcers.

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