Oclacitinib
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- $34 - $2395.3
- Product name: Oclacitinib
- CAS: 1208319-26-9
- MF: C15H23N5O2S
- MW: 337.44
- EINECS:950-980-7
- MDL Number:MFCD25976611
- Synonyms:PF-03394197 (oclacitinib);Oclacitinib PF-03394197;JAKi;trans-N-Methyl-4-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-cyclohexanemethanesulfonamide;CyclohexaneMethanesulfonaMide, N-Methyl-4-(Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMino)-, trans-;N-methyl-1-((1r,4r)-4-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamide;N-Methyl-1-(trans-4-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclohexyl)methanesulfonamide;Oclacitinib
22 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- Crysdot
- DC Chemicals
- TRC
Package
- 1mg
- 2mg
- 5MG
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- 5g
- ManufacturerAK Scientific
- Product number4057DF
- Product descriptionOclacitinib
- Packaging50mg
- Price$785
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5752
- Product descriptionOclacitinib
- Packaging50mg
- Price$968
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0002505
- Product descriptionOCLACITINIB 95.00%
- Packaging5MG
- Price$499.1
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5960
- Product descriptionPF-03394197(Oclacitinib)
- Packaging5mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146233
- Product descriptionPF-03394197(Oclacitinib) >98%
- Packaging100mg
- Price$765
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146233
- Product descriptionPF-03394197(Oclacitinib) >98%
- Packaging250mg
- Price$1208.7
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146233
- Product descriptionPF-03394197(Oclacitinib) >98%
- Packaging1g
- Price$2395.3
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFO164866
- Product descriptionOclacitinib
- Packaging1mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFO164866
- Product descriptionOclacitinib
- Packaging2mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFO164866
- Product descriptionOclacitinib
- Packaging5mg
- Price$325
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFO164866
- Product descriptionOclacitinib
- Packaging10mg
- Price$460
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFO164866
- Product descriptionOclacitinib
- Packaging25mg
- Price$750
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18722
- Product descriptionOclacitinib ≥98%
- Packaging1mg
- Price$34
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18722
- Product descriptionOclacitinib ≥98%
- Packaging5mg
- Price$127
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18722
- Product descriptionOclacitinib ≥98%
- Packaging10mg
- Price$236
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18722
- Product descriptionOclacitinib ≥98%
- Packaging50mg
- Price$505
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 4057DF | Oclacitinib | 50mg | $785 | 2021-12-16 | Buy |
| AK Scientific | SYN5752 | Oclacitinib | 50mg | $968 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0002505 | OCLACITINIB 95.00% | 5MG | $499.1 | 2021-12-16 | Buy |
| ApexBio Technology | B5960 | PF-03394197(Oclacitinib) | 5mg | $140 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146233 | PF-03394197(Oclacitinib) >98% | 100mg | $765 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146233 | PF-03394197(Oclacitinib) >98% | 250mg | $1208.7 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb146233 | PF-03394197(Oclacitinib) >98% | 1g | $2395.3 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FO164866 | Oclacitinib | 1mg | $150 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FO164866 | Oclacitinib | 2mg | $200 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FO164866 | Oclacitinib | 5mg | $325 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FO164866 | Oclacitinib | 10mg | $460 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FO164866 | Oclacitinib | 25mg | $750 | 2021-12-16 | Buy |
| Cayman Chemical | 18722 | Oclacitinib ≥98% | 1mg | $34 | 2024-03-01 | Buy |
| Cayman Chemical | 18722 | Oclacitinib ≥98% | 5mg | $127 | 2024-03-01 | Buy |
| Cayman Chemical | 18722 | Oclacitinib ≥98% | 10mg | $236 | 2024-03-01 | Buy |
| Cayman Chemical | 18722 | Oclacitinib ≥98% | 50mg | $505 | 2024-03-01 | Buy |
Properties
Melting point :226-228°C
Density :1.316±0.06 g/cm3(Predicted)
vapor pressure :0Pa at 20-25℃
storage temp. :Refrigerator, Under inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly, Sonicated)
pka :11.59±0.40(Predicted)
form :Solid
color :Off-White to Pale Beige
InChI :InChI=1S/C15H23N5O2S/c1-16-23(21,22)9-11-3-5-12(6-4-11)20(2)15-13-7-8-17-14(13)18-10-19-15/h7-8,10-12,16H,3-6,9H2,1-2H3,(H,17,18,19)/t11-,12-
InChIKey :HJWLJNBZVZDLAQ-HAQNSBGRSA-N
SMILES :[C@@H]1(CS(NC)(=O)=O)CC[C@@H](N(C)C2N=CN=C3NC=CC3=2)CC1
LogP :1.38 at 35℃ and pH7
Density :1.316±0.06 g/cm3(Predicted)
vapor pressure :0Pa at 20-25℃
storage temp. :Refrigerator, Under inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly, Sonicated)
pka :11.59±0.40(Predicted)
form :Solid
color :Off-White to Pale Beige
InChI :InChI=1S/C15H23N5O2S/c1-16-23(21,22)9-11-3-5-12(6-4-11)20(2)15-13-7-8-17-14(13)18-10-19-15/h7-8,10-12,16H,3-6,9H2,1-2H3,(H,17,18,19)/t11-,12-
InChIKey :HJWLJNBZVZDLAQ-HAQNSBGRSA-N
SMILES :[C@@H]1(CS(NC)(=O)=O)CC[C@@H](N(C)C2N=CN=C3NC=CC3=2)CC1
LogP :1.38 at 35℃ and pH7
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Janus-associated kinases (JAKs) are cytoplasmic tyrosine kinases that are required for activating the signaling of certain cytokines and growth factor receptors. Oclacitinib is an orally bioavailable, broad spectrum JAK inhibitor (IC50s = 10, 18, 99, and 84 nM for JAK1, JAK2, JAK3, and JAK4, respectively). It is specific for JAK isozymes against a large panel of other kinases. Oclacitinib blocks cell-based JAK signaling induced by IL-2, IL-4, IL-6, IL-13, or IL-31 with IC50 values ranging from 36 to 249 nM. Oral oclacitinib is used against atopic dermatitis with pruritus in dogs.More related product prices
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