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ChemicalBook CAS DataBase List 1-(4-fluorobenzoyl)cyclopropanecarboxylic acid

1-(4-fluorobenzoyl)cyclopropanecarboxylic acid synthesis

2synthesis methods
63131-29-3 Synthesis
METHYL 4-FLUOROBENZOYLACETATE

63131-29-3
179 suppliers
$14.00/1g

1-(4-fluorobenzoyl)cyclopropanecarboxylic acid

1191284-11-3
14 suppliers
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Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: potassium carbonate / methanol; dimethyl sulfoxide / 0.5 h / 20 °C
1.2: 48 h / 25 - 60 °C
2.1: lithium hydroxide / tetrahydrofuran

References:

Chen, Gen-Qiang;Tang, Xiang-Ying;Shi, Min [Chemical Communications,2012,vol. 48,# 17,p. 2340 - 2342]