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1-BOC-4-(2-METHYLPHENYL)-4-HYDROXYPIPERIDINE synthesis

3synthesis methods
79099-07-3 Synthesis
N-(tert-Butoxycarbonyl)-4-piperidone

79099-07-3
548 suppliers
$5.00/5g

1-BOC-4-(2-METHYLPHENYL)-4-HYDROXYPIPERIDINE

553630-96-9
21 suppliers
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Yield:553630-96-9 99%

Reaction Conditions:

Stage #1: 2-methylphenyl bromidewith n-butyllithium in tetrahydrofuran at -78; for 2 h;
Stage #2: N-tert-butyloxycarbonylpiperidin-4-one in tetrahydrofuran at -78 - 20;

References:

Davidson, Ross;Hsu, Yu-Ting;Batchelor, Thomas;Yufit, Dmitry;Beeby, Andrew [Dalton Transactions,2016,vol. 45,# 28,p. 11496 - 11507]

109384-19-2 Synthesis
N-BOC-4-Hydroxypiperidine

109384-19-2
481 suppliers
$5.00/1g

91994-11-5 Synthesis
5,5-Dimethyl-2-(2-methylphenyl)-1,3,2-dioxaborinane

91994-11-5
32 suppliers
$45.00/50mg

1-BOC-4-(2-METHYLPHENYL)-4-HYDROXYPIPERIDINE

553630-96-9
21 suppliers
inquiry