2-METHYL-5-NITRO-PYRIDINE-BORONIC ACID PINACOL ESTER synthesis

Yield: 82%

Reaction Conditions:

with dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂;potassium acetate in 1,4-dioxane at 100; for 3 h;Inert atmosphere;

References:

Nishiguchi, Gisele A.;Rico, Alice;Tanner, Huw;Aversa, Robert J.;Taft, Benjamin R.;Subramanian, Sharadha;Setti, Lina;Burger, Matthew T.;Wan, Lifeng;Tamez, Victoriano;Smith, Aaron;Lou, Yan;Barsanti, Paul A.;Appleton, Brent A.;Mamo, Mulugeta;Tandeske, Laura;Dix, Ina;Tellew, John E.;Huang, Shenlin;Mathews Griner, Lesley A.;Cooke, Vesselina G.;Van Abbema, Anne;Merritt, Hanne;Ma, Sylvia;Gampa, Kalyani;Feng, Fei;Yuan, Jing;Wang, Yingyun;Haling, Jacob R.;Vaziri, Sepideh;Hekmat-Nejad, Mohammad;Jansen, Johanna M.;Polyakov, Valery;Zang, Richard;Sethuraman, Vijay;Amiri, Payman;Singh, Mallika;Lees, Emma;Shao, Wenlin;Stuart, Darrin D.;Dillon, Michael P.;Ramurthy, Savithri [Journal of Medicinal Chemistry,2017,vol. 60,# 12,p. 4869 - 4881]