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4-Chloro-7-methyl-N-propyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine synthesis

2synthesis methods
84955-31-7 Synthesis
2-Amino-4-chloropyrrolo[2,3-d]pyrimidine

84955-31-7
193 suppliers
$5.00/250mg

4-Chloro-7-methyl-N-propyl-7H-pyrrolo[2,3-d]pyrimidin-2-amine

1380343-09-8
5 suppliers
inquiry

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Yield:-

Steps:

Multi-step reaction with 3 steps
1: triethylamine / dichloromethane / -30 - 20 °C
2: potassium carbonate / N,N-dimethyl-formamide / 15 h / 20 °C
3: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.17 h / 0 °C / Inert atmosphere

References:

WO2012/74999,2012,A1