1H-Pyrazol-5-ol, 1-ethyl-3-(2-pyridinyl)- synthesis
- Product Name:1H-Pyrazol-5-ol, 1-ethyl-3-(2-pyridinyl)-
- CAS Number:1279105-73-5
- Molecular formula:C10H11N3O
- Molecular Weight:189.21
26510-52-1
131 suppliers
$10.00/250mg
6629-60-3
94 suppliers
$52.00/5g
1279105-73-5
0 suppliers
inquiry
Yield:1279105-73-5 40%
Reaction Conditions:
in ethanol at 80;
Steps:
1.3
3-Oxo-3-pyridin-2-yl-propionic acid ethyl ester (500 mg, 2.59 mmol) and ethylhydrazine oxalate (389 mg, 2.59 mmol) was dissolved in EtOH, and stirred at 80° C. Upon completion, the EtOH was removed and triturated with Et2O to give 2-Ethyl-5-pyridin-2-yl-2H-pyrazol-3-ol (200 mg, 40%) as a white solid.
References:
US2011/71150,2011,A1 Location in patent:Page/Page column 26-27