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ChemicalBook CAS DataBase List 2-(2,3-DICHLOROPHENYL)PROPIONIC ACID

2-(2,3-DICHLOROPHENYL)PROPIONIC ACID synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: sulfuric acid / 2 h / Reflux
2: sodium hydride / N,N-dimethyl-formamide / 2 h / 0 °C
3: lithium hydroxide / tetrahydrofuran; water / 20 °C

References:

Ann, Jihyae;Bahrenberg, Gregor;Blumberg, Peter M.;Choi, Sun;Christoph, Thomas;Do, Nayeon;Frank-Foltyn, Robert;Ha, Heejin;Jeong, Jin Ju;Kang, Jin Mi;Kim, Changhoon;Kwon, Sun Ok;Lee, Jeewoo;Lee, Sunho;Lesch, Bernhard;Stockhausen, Hannelore;Vu, Thi Ngoc Lan;Yoon, Sanghee [Bioorganic and Medicinal Chemistry Letters,2021,vol. 48,art. no. 128266]

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