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2-(4-CHLOROPHENYL)-2-PHENYLACETIC ACID synthesis

10synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: 1.) NaH / 1.) THF, 55 deg C, 6 h, 2.) 55 deg C, 16 h
2: BF3*Et2O / benzene / 0.08 h
3: Jones' reagent, isopropyl alcohol / acetone / -10 °C

References:

Halterman, Ronald L.;McEvoy, Marjorie A. [Journal of the American Chemical Society,1990,vol. 112,# 18,p. 6690 - 6695]

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