ChemicalBook CAS DataBase List 2-Amino-5-chlorobenzenesulfonamide

2-Amino-5-chlorobenzenesulfonamide synthesis

8synthesis methods

Product Name:2-Amino-5-chlorobenzenesulfonamide
CAS Number:5790-69-2
Molecular formula:C6H7ClN2O2S
Molecular Weight:206.65

3306-62-5 Synthesis

3306-62-5
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$5.00/100mg

5790-69-2
78 suppliers
$48.00/250 mg

Yield:5790-69-2 95%

Reaction Conditions:

with N-chloro-succinimide in chloroform for 3 h;Reflux;Solvent;

Steps:

1
o-Aminobenzenesulfonamide (1.72g) was mixed with NCS (1.32g, 1.0 equivalent), dissolved in chloroform, stirred at reflux temperature for 3 hours, and then purified by column chromatography to prepare compound II2-amino-5- Chlorobenzenesulfonamide 1.96g, the yield of this step is 95%, the purity is greater than 99%, the experimental value of mass spectrometry: 206.9, the mass spectrum is shown in Figure 1.

References:

Soochow University (Suzhou);Qiao Chunhua;Xu Yiwen;Shen Bei CN110903264, 2020, A Location in patent:Paragraph 0017; 0019-0020

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