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2-Benzothiazolebutanoicacid(9CI) synthesis

11synthesis methods
21344-52-5 Synthesis
2-Benzothiazolebutyronitrile(8CI)

21344-52-5
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Yield:41387-91-1 93 %

Reaction Conditions:

with hydrogenchloride in 1,4-dioxane at 80;Reflux;Schlenk technique;

References:

Zhou, Wuxin;Long, Yang;Xiang, Haifeng;Xu, Buyi;Zhou, Xiangge [Journal of Organic Chemistry,2023,vol. 88,# 7,p. 4875 - 4879] Location in patent:supporting information