2-Fluorobenzoic acid synthesis
- Product Name:2-Fluorobenzoic acid
- CAS Number:445-29-4
- Molecular formula:C7H5FO2
- Molecular Weight:140.11
446-52-6
424 suppliers
$6.00/25g
445-29-4
412 suppliers
$5.00/10g
Yield:445-29-4 95%
Reaction Conditions:
with oxygen;Cu(OAc)2*H2O;Co(OAc)2.4H2O in lithium hydroxide monohydrate at 70; under 760.051 Torr; for 12 h;
Steps:
10 Example 10 Preparation of o-fluorobenzoic acid by oxidation of o-fluorobenzaldehyde
Under normal pressure oxygen, water (2mL), o-fluorobenzaldehyde (1mmol), Cu(OAc)2· H2O (0.03mmol, 3% mole fraction) and Co(OAc)2· 4H2O (0.03mmol, 3% mole fraction) was added to a 15mL glass reaction tube, and an oxygen balloon was connected.The reaction tube was placed in an oil bath heated to 70°C in advance and stirred for 12 hours. After the reaction was completed, the temperature was lowered, the crude product solid was separated by centrifugation, and then ultrasonically washed with 3 mL of water, centrifuged and dried to constant weight to obtain the target product. The separation yield was 95 %.
References:
CN111116348,2020,A Location in patent:Paragraph 0030-0031
446-51-5
242 suppliers
$8.00/5g
445-29-4
412 suppliers
$5.00/10g
95-52-3
288 suppliers
$10.00/5g
445-29-4
412 suppliers
$5.00/10g
