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(2-OXOAZEPAN-1-YL)ACETIC ACID synthesis

3synthesis methods
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Yield:35048-56-7 65%

Reaction Conditions:

with sulfuric acid;palladium;lithium bromide in 1-methyl-pyrrolidin-2-one at 60; under 45004.5 Torr; for 16 h;Inert atmosphere;Autoclave;Temperature;

References:

Hancker, S?ren;Kreft, Stefanie;Neumann, Helfried;Beller, Matthias [Organic Process Research and Development,2017,vol. 21,# 12,p. 2045 - 2051] Location in patent:supporting information