ChemicalBook CAS DataBase List 2-Phenylacetamide

2-Phenylacetamide synthesis

13synthesis methods

Product Name:2-Phenylacetamide
CAS Number:103-81-1
Molecular formula:C8H9NO
Molecular Weight:135.16

Synthesis of 2-phenylacetamide: Add concentrated hydrochloric acid to phenylacetonitrile, stir to dissolve, and react at 50°C for half an hour. Then slowly add water under cooling to separate out crystals, filter after cooling, wash with ice water to obtain crude product. The crude product was washed with sodium carbonate solution, then washed with ice water, and dried to obtain purer phenylacetamide.

140-29-4
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103-81-1
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$13.00/5g

Yield:103-81-1 100%

Reaction Conditions:

with Acetaldehyde oxime in methanol at 65; for 4 h;

Steps:

General procedure: A typical reaction was carried out in a 10 mL flask. Benzonitrile (2 mmol), Cu^II-4 ? (0.2 g), acetaldoxime (6 mmol) and MeOH (4 mL) were stirred at 65 °C for 4 h. The solid was filtered, washed with MeOH and the filtrate evaporated. The residue was subjected to GC-MS analysis and NMR spectroscopy. The filtered catalyst can be recycled after drying at about 150 °C for 1 h.

References:

Kiss, árpád;Hell, Zoltán [Tetrahedron Letters,2011,vol. 52,# 45,p. 6021 - 6023] Location in patent:experimental part

122-78-1
309 suppliers
$10.00/5g

103-81-1
339 suppliers
$13.00/5g

References

7028-48-0
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inquiry

103-81-1
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References

536-74-3 Synthesis

536-74-3
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103-81-1
339 suppliers
$13.00/5g

References

103-80-0
307 suppliers
$13.00/25g

103-81-1
339 suppliers
$13.00/5g

References

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