3-(3-METHOXY-PHENYL)-2-METHYL-PROPIONIC ACID synthesis
- Product Name:3-(3-METHOXY-PHENYL)-2-METHYL-PROPIONIC ACID
- CAS Number:61227-51-8
- Molecular formula:C11H14O3
- Molecular Weight:194.23
Yield:61227-51-8 86 %
Reaction Conditions:
Stage #1: propionic acidwith n-butyllithium;diisopropylamine in tetrahydrofuran at -78 - 40;Inert atmosphere;
Stage #2: m-methoxybenzyl chloride in tetrahydrofuran at 0 - 20;
References:
Dong, Zi-Yu;Zhao, Jia-Hui;Wang, Peng;Yu, Jin-Quan [Organic Letters,2022,vol. 24,# 42,p. 7732 - 7736] Location in patent:supporting information
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