3-[(4-METHOXYPHENYL)SULFONYL]PROPANOIC ACID synthesis
- Product Name:3-[(4-METHOXYPHENYL)SULFONYL]PROPANOIC ACID
- CAS Number:91062-23-6
- Molecular formula:C10H12O5S
- Molecular Weight:244.26
1950-68-1
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79-10-7
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91062-23-6
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$378.00/1g
Yield:91062-23-6 90%
Reaction Conditions:
in water monomer at 85; for 10 h;
Steps:
6 Example 6:
Take a 25 mL single-necked round bottom flask,Weigh p-methoxybenzenesulfonylhydrazide (1 mmol, 202.2 mg) was added,Acrylic acid (2 mmol, 0.14 mL) was then measured,Add 1mL of water, add the appropriate type of magnet,Device condenser tube reflux. 85oC oil bath heating reaction 10 h.After the reaction, stop heating, natural cooling to room temperature,The pH of the solution was adjusted to 6, EtOAc (100 mL x 3) with 1 mol / L HCl,The organic phases were combined and the organic phase was washed with saturated brine to collect the combined organic phases,Dried over anhydrous sodium sulfate for half an hour,Spin off the solvent to get 3 - p - methoxybenzenesulfonyl propionic acid, white solid 219.8mg, the yield of 90%.
References:
CN106631927,2017,A Location in patent:Paragraph 0019
98-68-0
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91062-23-6
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13739-36-1
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91062-23-6
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91062-23-6
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91062-23-6
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