3-n-Propyl-2-thiohydantoin, 95% synthesis
1synthesis methods
- Product Name:3-n-Propyl-2-thiohydantoin, 95%
- CAS Number:65710-56-7
- Molecular formula:C6H10N2OS
- Molecular Weight:158.2214
Yield:65710-56-7 99%
Reaction Conditions:
Stage #1: glycine ethyl ester hydrochloridewith triethylamine in diethyl ether; for 0.5 h;Inert atmosphere;
Stage #2: n-Propyl isothiocyanate in diethyl ether; for 24 h;Inert atmosphere;Reflux;
References:
Gutirrez, Sara;Martnez-Lpez, David;Morn, Mara;Sucunza, David;Sampedro, Diego;Domingo, Alberto;Salgado, Antonio;Vaquero, Juan J. [Chemistry - A European Journal,2015,vol. 21,# 51,p. 18758 - 18763] Location in patent:supporting information