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3-OXO-4-M-TOLYL-BUTYRIC ACID ETHYL ESTER synthesis

2synthesis methods
-

Yield:83823-59-0 92%

Steps:

109.l 3-Methyl-b-oxobenzenebutanoic Acid Ethyl Ester

Example 109, Part A 3-Methyl-b-oxobenzenebutanoic Acid Ethyl Ester m-tolylacetic acid (2.0 g, 13.33 mmol) was subjected to the same conditions as outlined in method A3 (example 3) to yield the title compound (2.7 g, 92%). 1H NMR (CDCl3): 7.25 (m, 1H), 7.1 (d, 1H), 7.0 (m, 2H), 4.2 (q, 2H), 3.8 (s, 2H), 3.4 (s, 2H), 2.4 (s, 3H), 1.2 (t, 3H).

References:

US2002/40022,2002,A1

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