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4-(3-CHLORO-PHENYL)-PIPERIDIN-4-OL synthesis

3synthesis methods
871112-37-7 Synthesis
1-N-BOC-4-(3-CHLOROPHENYL)-4-HYDROXYPIPERIDINE

871112-37-7
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Yield:70558-16-6 97%

Reaction Conditions:

with hydrogenchloride in 1,4-dioxane at 20; for 2 h;

References:

Fyfe, Tim J.;Kellam, Barrie;Sykes, David A.;Capuano, Ben;Scammells, Peter J.;Lane, J. Robert;Charlton, Steven J.;Mistry, Shailesh N. [Journal of Medicinal Chemistry,2019,vol. 62,# 21,p. 9488 - 9520]

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