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4-METHOXY-3'-METHYLBENZHYDROL synthesis

3synthesis methods
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Yield:37825-77-7 90%

Reaction Conditions:

Stage #1: 1-bromo-4-methoxy-benzenewith magnesium in tetrahydrofuran;ethylene dibromide at 20; for 1 h;Inert atmosphere;
Stage #2: m-tolyl aldehyde in tetrahydrofuran;ethylene dibromide at 20;Inert atmosphere;

References:

Lanzi, Matteo;Merad, Jérémy;Boyarskaya, Dina V.;Maestri, Giovanni;Allain, Clémence;Masson, Géraldine [Organic Letters,2018,vol. 20,# 17,p. 5247 - 5250] Location in patent:supporting information