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4TERTBUTYL4AMINOBIPHENYL synthesis

8synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: n-BuLi / hexane; tetrahydrofuran / 1 h / -78 °C
1.2: triisopropylborate / hexane; tetrahydrofuran / 2 h / 20 °C
1.3: 85 percent / Ba(OH)2*8H2O; Pd(PPh3)4 / hexane; tetrahydrofuran; 1,2-dimethoxy-ethane / 80 °C
2.1: 87 percent / SnCl2*2H2O / ethanol; ethyl acetate / Heating

References:

Glende, Carsten;Klein, Markus;Schmitt, Heimo;Erdinger, Lothar;Boche, Gernot [Mutation Research - Genetic Toxicology and Environmental Mutagenesis,2002,vol. 515,# 1-2,p. 15 - 38]