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(3S,4S,6R)-5-{2-Oxo-hexahydro-1H-thieno[3,4-d]imidazolidin-4-yl}-N-(prop-2-en-1-yl)pentanamide synthesis

1synthesis methods
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Yield:92924-45-3 55%

Reaction Conditions:

with 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-morpholinium chloride in water;acetonitrile at 20; for 16 h;

References:

Bhushan, Bhaskar;Lin, Yuya A.;Bak, Martin;Phanumartwiwath, Anuchit;Yang, Nan;Bilyard, Matthew K.;Tanaka, Tomonari;Hudson, Kieran L.;Lercher, Lukas;Stegmann, Monika;Mohammed, Shabaz;Davis, Benjamin G. [Journal of the American Chemical Society,2018,vol. 140,# 44,p. 14599 - 14603] Location in patent:supporting information