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3-(TERT-BUTYL)-1-PHENYL-1H-PYRAZOLE-5-CARBOXYLIC ACID synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1.1: sodium / ethanol / 0 - 20 °C
2.1: methanol / 1.5 h / 0 - 20 °C
2.2: 2 h / Reflux
3.1: sodium hydroxide / water / 2 h / 80 °C

References:

Deng, Xi-Le;Xie, Jin;Li, Yong-Qiang;Yuan, De-Kai;Hu, Xue-Ping;Zhang, Li;Wang, Qing-Min;Chi, Ming;Yang, Xin-Ling [Chinese Chemical Letters,2016,vol. 27,# 4,p. 566 - 570]

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