Benzeneacetonitrile, 2-fluoro-4-methyl- (9CI) synthesis
1synthesis methods
- Product Name:Benzeneacetonitrile, 2-fluoro-4-methyl- (9CI)
- CAS Number:518070-26-3
- Molecular formula:C9H8FN
- Molecular Weight:149.16
Yield:518070-26-3 91%
Reaction Conditions:
with dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane;bis(η3-allyl-μ-chloropalladium(II)) in 1,3,5-trimethyl-benzene at 20 - 140; for 5.16667 h;Inert atmosphere;Sealed tube;chemoselective reaction;
References:
Shang, Rui;Ji, Dong-Sheng;Chu, Ling;Fu, Yao;Liu, Lei [Angewandte Chemie - International Edition,2011,vol. 50,# 19,p. 4470 - 4474] Location in patent:supporting information; experimental part