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ChemicalBook CAS DataBase List Dofetilide

Dofetilide synthesis

7synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 72 percent / H2 / Raney nickel / ethanol / 16 h / 2280 Torr / Ambient temperature
2: 51 percent / CH2Cl2 / Ambient temperature

References:

Cross;Arrowsmith;Thomas;Gwilt;Burges;Higgins [Journal of Medicinal Chemistry,1990,vol. 33,# 4,p. 1151 - 1155]

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