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ChemicalBook CAS DataBase List Irinotecan hydrochloride

Irinotecan hydrochloride synthesis

7synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1.1: dichloromethane; acetonitrile / 20 - 70 °C
1.2: 20 °C
2.1: triethylamine; pyridine; acetamide / dichloromethane / 2 h / 30 - 40 °C / Inert atmosphere
3.1: hydrogenchloride / water

References:

CADILA HEALTHCARE LIMITED US2011/144342, 2011, A1

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