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ChemicalBook CAS DataBase List Methyl 3-(4-bromomethyl)cinnamate

Methyl 3-(4-bromomethyl)cinnamate synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: thionyl chloride / 1 h / 0 °C
1.2: 4 h / 65 °C
2.1: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / tetrachloromethane / 2 h / 20 °C

References:

Ling, Yong;Gao, Wei-Jie;Ling, Changchun;Liu, Ji;Meng, Chi;Qian, Jianqiang;Liu, Siqun;Gan, Huiling;Wu, Hongmei;Tao, Jinhua;Dai, Hong;Zhang, Yanan [European Journal of Medicinal Chemistry,2019,vol. 168,p. 515 - 526]

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