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ChemicalBook CAS DataBase List MIDODRINE

MIDODRINE synthesis

2synthesis methods
tert-butyl (2-((2-(2,5-dimethoxyphenyl)-2-oxoethyl)amino)-2-oxoethyl)carbamate

176851-43-7
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Yield:42794-76-3 75%

Reaction Conditions:

with hydrogenchloride in methanol;water at 20; for 2 h;Schlenk technique;Inert atmosphere;

References:

Caldwell, Nicola;Jamieson, Craig;Simpson, Iain;Tuttle, Tell [Organic Letters,2013,vol. 15,# 10,p. 2506 - 2509] Location in patent:supporting information

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