ChemicalBook CAS DataBase List o-Toluoyl chloride

o-Toluoyl chloride synthesis

11synthesis methods

Product Name:o-Toluoyl chloride
CAS Number:933-88-0
Molecular formula:C8H7ClO
Molecular Weight:154.59

118-90-1 Synthesis

118-90-1
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933-88-0
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$10.00/1g

Yield:933-88-0 99.7%

Reaction Conditions:

with thionyl chloride;N,N-dimethyl-formamide at 90; for 3 h;Concentration;Reagent/catalyst;Temperature;

Steps:

1 Preparation of compounds of formula (III) - ortho
In a 1000 ml reaction flask equipped with a thermometer, a stirrer, a condenser, and an exhaust gas absorption device, 540.56 g of o-toluic acid, 571.0 g of thionyl chloride and 2 g of N, N-dimethylformamide were placed and heated to 90 ° C, the reaction was stirred 3h, the reaction was completely transparent, the excess of thionyl chloride removed under reduced pressure to give o-methyl benzoyl chloride 612.7g, purity 98.8%, the yield of 99.7%.

References:

Zibo Feiyuan Chemical Co., Ltd.;Cui Liyan;Xiao Yuling;Xia Kai CN107417518, 2017, A Location in patent:Paragraph 0021-0023

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95-47-6 Synthesis