Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
Inquriy
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
My chemicalbook

Welcome back!

Structured search
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
ChemicalBook CAS DataBase List Trimethylsilyl cyanide

Trimethylsilyl cyanide synthesis

13synthesis methods
Trimethylsilyl cyanide, (CH3)3 Si-CN, is obtained by reacting trimethylsilyl chloride with an approximately equimolar amount of an alkali metal cyanide in the absence of water and in the presence of catalytic, sub-stoichiometric amounts of both an alkali metal iodide and N-methylpyrrolidone, at a temperature of from 15°-25° C.
Trimethylsilyl cyanide is very toxic. All reactions in this sequence should be carried out in a hood.
Preparation of trimethylsilyl cyanide
TRIMETHYLSILYL CYANIDE: CYANOSILATION OF p-BENZOQUINONE
18306-29-1 Synthesis
Bis(trimethylsilyl)sulfate

18306-29-1
103 suppliers
$13.00/5g

POTASSIUM CYANIDE

151-50-8
4 suppliers
$47.79/100g

Trimethylsilyl cyanide

7677-24-9
367 suppliers
$19.00/5g

-

Yield:7677-24-9 96%

Reaction Conditions:

with 1-methyl-pyrrolidin-2-one at 200;

References:

Kantlehner, Willi;Haug, Erwin;Mergen, Walter W. [Synthesis,1980,# 6,p. 460 - 461]

Chlorotrimethylsilane

75-77-4
558 suppliers
$5.04/10

POTASSIUM CYANIDE

151-50-8
4 suppliers
$47.79/100g

Trimethylsilyl cyanide

7677-24-9
367 suppliers
$19.00/5g

References
Chlorotrimethylsilane

75-77-4
558 suppliers
$5.04/10

143-33-9 Synthesis
Sodium cyanide

143-33-9
5 suppliers
$10.00/1g

Trimethylsilyl cyanide

7677-24-9
367 suppliers
$19.00/5g

References
Benzyl thiocyanate

3012-37-1
124 suppliers
$14.00/1g

81290-20-2 Synthesis
(Trifluoromethyl)trimethylsilane

81290-20-2
393 suppliers
$13.00/1g

Trimethylsilyl cyanide

7677-24-9
367 suppliers
$19.00/5g

BENZYL TRIFLUOROMETHYL SULFIDE

351-60-0
32 suppliers
$52.00/5g

References
N-OCTYL THIOCYANATE

19942-78-0
21 suppliers
inquiry

81290-20-2 Synthesis
(Trifluoromethyl)trimethylsilane

81290-20-2
393 suppliers
$13.00/1g

Trimethylsilyl cyanide

7677-24-9
367 suppliers
$19.00/5g

Octane, 1-[(trifluoromethyl)thio]-

134776-65-1
1 suppliers
inquiry

References

Trimethylsilyl cyanide Related Search:

(Trifluoromethyl)trimethylsilane tert-Butyldimethylsilyl chloride TRIMETHYLSILANE Phosphonitrilic chloride trimer Tosylmethyl isocyanide PHENYLTRIMETHYLSILANE Trimethylsilyl trifluoromethanesulfonate Trimethoxysilane Trimethyl thiazole Trimethoxysilylpropanethiol