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ChemicalBook CAS DataBase List Zolpidem

Zolpidem synthesis

2synthesis methods
-

Yield:-

Reaction Conditions:

Stage #1: dimethyl-(6-methyl-2-p-tolylimidazo[1,2-a]pyridin-3-ylmethyl)-aminewith methyl iodide in ethanol at 20; for 24 h;
Stage #2: potassium cyanide in ethanol;water; for 4 h;Heating;

References:

Lange;Karolak-Wojciechowska;Wejroch;Rump [Acta poloniae pharmaceutica,2001,vol. 58,# 1,p. 43 - 52]

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