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Pharmaceutical intermediates

Pharmaceutical intermediates are the drugs used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry.

What is 2,4,6-triphenylpyrylium fluoroborate?

2,4,6-Triphenylpyrylium fluoroborate can be used as photocatalyst to catalyze the photoinduced electron-transfer (PET)-promoted reaction.

Jan 7,2020  Pharmaceutical intermediates

2,4,5-Trichloropyrimidine-Application

2,4,5-Trichloropyrimidine is used in the synthesis of potent and selective anaplastic lymphoma kinase (ALK-5) inhibitors, used as an anti-tumor treatment. It is also used in the synthesis of EGFR inhi

Dec 30,2019  Pharmaceutical intermediates

the synthesis of 2,6-Pyridinedicarbonitrile

2,6-Pyridinedicarbonitrile is a heterocyclic dinitrile, which may be used to synthesize bis-tetrazoles and pyridine-based tridentate ligand 2,6-bis(α-aminoisopropyl)pyridine.

Dec 27,2019  Pharmaceutical intermediates

Synthesis of 2-Deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate

2-Deoxy-2,2-difluoro-D-erythro-pentofuranos-1-ulose-3,5-dibenzoate (CAS: 122111-01-7) is a compound useful in organic synthesis and it is the key intermediate of gemcitabine.

Dec 27,2019  Pharmaceutical intermediates

Tautomerism characteristics of 4-pyrimidone

Pyrimidone is the name given to either of two heterocyclic compounds with the formula C4H4N2O: 2-pyrimidone and 4-pyrimidone.

Dec 27,2019  Pharmaceutical intermediates

Applications of 3-Fluoro-4-(4-methylpiperazin-1-yl)aniline

3-Fluoro-4-(4-methylpiperazin-1-yl)aniline is an important organic building block to synthetize substituted aniline products.

Dec 26,2019  Pharmaceutical intermediates

The role of 5-chloro-2-phenoxyphenylacetic acid as asenapine intermediate

5-chloro-2-phenoxyphenylacetic acid is the intermediate of asenapine synthesis, and Marco talked about the synthesis routes starting from 5-chloro-2-phenoxyphenylacetic acid as shown in scheme 1[2].

Dec 23,2019  Pharmaceutical intermediates

1-Methyl-aminomethyl naphthalene-Application

1-Methyl-aminomethyl naphthalene has been used as reagent for the determination of isocyanates in air by UV or fluorescence detection.

Dec 19,2019  Pharmaceutical intermediates

The application of methyl 5-chloro-6-methylpyrazine-2-carboxylate in physiology

The N-methyl-d-aspartate (NMDA) receptor is arguably an important signaling mechanism in the human brain and NMDA receptors play a critical role in regulating the strength of synapses, that is, in reg

Dec 18,2019  Pharmaceutical intermediates

4-Chloro-7H-pyrrolo[2,3-d] pyrimidine— a medical intermediate

Being an important intermediate in medicine, 4-Chloro-7H-pyrrolo[2,3-d] pyrimidine had been widely used in the synthesis of many pharmaceutical intermediates at home and abroad.

Dec 18,2019  Pharmaceutical intermediates
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