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1000164-43-1

1000164-43-1 Structure

1000164-43-1 Structure
IdentificationBack Directory
[Name]

FMOC-SER(TBU)-SER(PSIME,MEPRO)-OH
[CAS]

1000164-43-1
[Synonyms]

FMOC-SER(TBU)-SER(PSIME,MEPRO)-OH
Fmoc-Ser(tBu)-Ser[Ψ(Me,Me)Pro]-OH
Fmoc-Ser(OtBu)-Ser{psi(Me,Me)pro}-OH
Fmoc-L-Ser(tBu)-L-Ser[PSI(Me,Me)Pro]-OH
Fmoc-Ser(tBu)-Ser[Psi(Me,Me)Pro]-OH≥ 98.5% (HPLC)
(9H-Fluoren-9-yl)MethOxy]Carbonyl Ser(tBu)-SerPsi(Me, Me)Pro-OH
(4S)-3-(FMoc-Ser(tBu))-2,2-diMethyl-oxazolidine-4-carboxylic acid
(S)-3-[Nα-(9-Fluorenylmethyloxycarbonyl)-O-tert-butyl-L-serinyl]-2,2-dimethyloxazolidine-4-carboxylic acid
(4S)-3-[(2S)-3-(tert-butoxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoyl]-2,2-dimethyl-1,3-oxazolidine-4-carboxylic acid
(4S)-3-[(2S)-3-(1,1-Dimethylethoxy)-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-1-oxopropyl]-2,2-dimethyl-4-oxazolidinecarboxylic acid
(4S)-3-[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[(2-methylpropan-2-yl)oxy]propanoyl]-2,2-dimethyl-1,3-oxazolidine-4-carboxylic acid
4-Oxazolidinecarboxylic acid, 3-[(2S)-3-(1,1-dimethylethoxy)-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-1-oxopropyl]-2,2-dimethyl-, (4S)-
[Molecular Formula]

C28H34N2O7
[MDL Number]

MFCD01634919
[MOL File]

1000164-43-1.mol
[Molecular Weight]

510.58
Chemical PropertiesBack Directory
[Boiling point ]

716.2±60.0 °C(Predicted)
[density ]

1.240±0.06 g/cm3(Predicted)
[storage temp. ]

Store at +2°C to +8°C.
[form ]

powder
[pka]

3.03±0.40(Predicted)
[color ]

White to off-white
[Major Application]

peptide synthesis
[InChIKey]

OXEDICXRSSILSN-GOTSBHOMSA-N
[SMILES]

O1C[C@@H](C(O)=O)N(C(=O)[C@@H](NC(OCC2C3=C(C=CC=C3)C3=C2C=CC=C3)=O)COC(C)(C)C)C1(C)C
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H319-H335-H302+H312+H332-H315
[Precautionary statements ]

P280-P301+P312-P362+P364
[WGK Germany ]

WGK 2
[HS Code ]

2934999090
[Storage Class]

11 - Combustible Solids
Questions And AnswerBack Directory
[Purity]

≥99%
Hazard InformationBack Directory
[Description]

Fmoc-Ser(Tbu)-Ser(Psime,Mepro)-OH is mainly used in the synthesis of peptides, including GLP-1(1-37) polypeptide, Tirzepatide and acylated peptides.
[Chemical Properties]

White to off-white powder
[Uses]

Fmoc-Ser(tBu)-Ser(PSiMe,MePro)-OH is used as a reactant in the synthesis of peptides and proteins.
[General Description]

Fmoc-Ser(tBu)-Ser(Psi(Me,Me)pro)-OH (1000164-43-1), also known as Fmoc-Ser(Tbu)-Ser(Psime,Mepro)-OH, is a high-purity dipeptide derivative commonly used in peptide synthesis. The introduction of the Psi(Me,Me)pro (ψ) structure into the molecule temporarily alters the conformation of the peptide backbone, disrupting the β-sheet structure, which helps to enhance the reaction rate and crude peptide yield in subsequent coupling steps.
[reaction suitability]

reaction type: Fmoc solid-phase peptide synthesis
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