| Identification | Back Directory | [Name]
1H-Pyrazole-1-acetamide, N-[3-(aminocarbonyl)-4,5,6,7-tetrahydrobenzo[b]thien-2-yl]-4-(hydroxymethyl)-3-(trifluoromethyl)- | [CAS]
1001019-46-0 | [Synonyms]
JAMI1001A
1H-Pyrazole-1-acetamide, N-[3-(aminocarbonyl)-4,5,6,7-tetrahydrobenzo[b]thien-2-yl]-4-(hydroxymethyl)-3-(trifluoromethyl)- | [Molecular Formula]
C16H17F3N4O3S | [MOL File]
1001019-46-0.mol | [Molecular Weight]
402.39 |
| Hazard Information | Back Directory | [Description]
JAMI1001A is a positive allosteric modulator of AMPA receptor. | [Uses]
JAMI1001A is a positive allosteric modulator of AMPA receptor. JAMI1001A efficaciously modulates AMPA receptor deactivation and desensitization of both flip and flop receptor isoforms[1]. | [References]
[1] Harms JE, et al. Functional analysis of a novel positive allosteric modulator of AMPA receptors derived from a structure-based drug design strategy. Neuropharmacology. 2013;64(1):45-52. DOI:10.1016/j.neuropharm.2012.06.008 |
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