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1001405-52-2

1001405-52-2 Structure

1001405-52-2 Structure
IdentificationBack Directory
[Name]

PSMα3
[CAS]

1001405-52-2
[Synonyms]

PSMα3
[Molecular Formula]

C128H192N28O30S
[MOL File]

1001405-52-2.mol
[Molecular Weight]

2635.17
Chemical PropertiesBack Directory
[Boiling point ]

2447.3±65.0 °C(Predicted)
[density ]

1.252±0.06 g/cm3(Predicted)
[form ]

Solid
[color ]

White to off-white
[Sequence]

{f}-Met-Glu-Phe-Val-Ala-Lys-Leu-Phe-Lys-Phe-Phe-Lys-Asp-Leu-Leu-Gly-Lys-Phe-Leu-Gly-Asn-Asn
Hazard InformationBack Directory
[Uses]

PSMα3 is a peptide for manipulating DCs to become tolerogenic for DC vaccination strategies. PSMα3 penetrates and modulates human monocyte-derived DCs by altering the TLR2- or TLR4-induced maturation, inhibiting pro- and anti-inflammatory cytokine production and reducing antigen uptake. PSMα3 is an important toxin released by the most virulent strains of methicillin-resistant Staphylococcus aureus (MRSA)[1][2].
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