| Identification | Back Directory | [Name]
Thieno[2,3-d]pyrimidin-4-amine, 5-(4-chlorophenyl)-N-methyl-N-(1-methyl-4-piperidinyl)- | [CAS]
1003091-20-0 | [Synonyms]
WAY-621360-A
H4R antagonist 3
Thieno[2,3-d]pyrimidin-4-amine, 5-(4-chlorophenyl)-N-methyl-N-(1-methyl-4-piperidinyl)- | [Molecular Formula]
C19H21ClN4S | [MOL File]
1003091-20-0.mol | [Molecular Weight]
372.91 |
| Chemical Properties | Back Directory | [Boiling point ]
531.9±50.0 °C(Predicted) | [density ]
1.293±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
8.69±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
H4R antagonist 3 (Example 18) is a histamine-4 receptor antagonist with an EC50 of ＜10 mM. H4R antagonist 3 can be used for the research of prevention of inflammatory, autoimmune, allergic, and ocular diseases[1]. | [References]
[1] Allen J. Borchardt, et al. Aminopyrimidine inhibitors of histamine receptors for the treatment of disease. Patent US20100063047A1. |
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