| Identification | Back Directory | [Name]
CP 67015 | [CAS]
100325-51-7 | [Synonyms]
CP-67
CP 67015
CCRIS 2955
CP67015,CP 67015
1-ethyl-6,8-difluoro-4-oxo-7-pyridin-4-ylquinoline-3-carboxylic acid
1-Ethyl-6,8-difluoro-1,4-dihydro-4-oxo-7-(4-pyridinyl)-3-quinolinecarboxylic acid
3-Quinolinecarboxylic acid, 1-ethyl-6,8-difluoro-1,4-dihydro-4-oxo-7-(4-pyridinyl)- | [Molecular Formula]
C17H12F2N2O3 | [MDL Number]
MFCD00887568 | [MOL File]
100325-51-7.mol | [Molecular Weight]
330.29 |
| Hazard Information | Back Directory | [Uses]
CP-67015, a quinolone antibiotic, is a potent topoisomerase II inhibitor. CP-67015 is a positive direct-acting mutagen in mammalian cells with both gene and chromosomal level effects[1]. | [in vivo]
CP-67015 (a single dose 1000 mg/kg or 500 mg/kg/day for 5 days; i.p.) induces chromosome damage in male CD-1 mice in mouse bone marrow cells[1]. | [IC 50]
Quinolone; Topoisomerase II | [References]
[1] Holden HE, et, al. Genetic profile of a nalidixic acid analog: a model for the mechanism of sister chromatid exchange induction. Environ Mol Mutagen. 1989;13(3):238-52. DOI:10.1002/em.2850130308 |
|
| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
| Company Name: |
CHEMICAL LAND21
|
| Tel: |
82- 2 -783 - 8063 |
| Website: |
www.chemicalland21.com |
|