| Identification | Back Directory | [Name]
BMS-593214 | [CAS]
1004551-40-9 | [Synonyms]
BMS-593214
[1,1'-Biphenyl]-4-carboxylic acid, 2'-[(6R,6aR,11bR)-2-(aminoiminomethyl)-6,6a,7,11b-tetrahydro-5H-indeno[2,1-c]quinolin-6-yl]-5'-hydroxy-4'-methoxy- | [Molecular Formula]
C31H27N3O4 | [MOL File]
1004551-40-9.mol | [Molecular Weight]
505.56 |
| Chemical Properties | Back Directory | [Boiling point ]
734.2±70.0 °C(Predicted) | [density ]
1.42±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
4.19±0.10(Predicted) | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Uses]
BMS-593214 is an active site-directed factor (F) VIIa inhibitor. BMS-593214 shows antithrombotic and antihaemostatic properties. BMS-593214 is a direct competitive inhibitor of human FVIIa and a non-competitive inhibitor of Viia-activated substrate FX. BMS-593214 prevents electroinduced carotid artery thrombosis (AT) and wire induced vena cava thrombosis (VT)[1]. | [References]
[1] Wong PC, et al. BMS-593214, an active site-directed factor VIIa inhibitor: enzyme kinetics, antithrombotic and antihaemostatic studies. Thromb Haemost. 2010 Aug;104(2):261-9. DOI:10.1160/TH10-01-0025 |
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| Company Name: |
BOC Sciences
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1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
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