| Identification | Back Directory | [Name]
2-Thiazolesulfonyl chloride | [CAS]
100481-09-2 | [Synonyms]
Thiazolesulfonyl chloride
2-THIAZOLESULFONYL CHLORIDE
thiazole-2-sulfonyl chloride
2-Thiazolesulfonylchloride(9CI)
1,3-thiazole-2-sulfonyl chloride
2-Thiazolesulfonyl chloride ISO 9001：2015 REACH | [Molecular Formula]
C3H2ClNO2S2 | [MDL Number]
MFCD08460252 | [MOL File]
100481-09-2.mol | [Molecular Weight]
183.64 |
| Chemical Properties | Back Directory | [Boiling point ]
328.5±25.0 °C(Predicted) | [density ]
1.687±0.06 g/cm3(Predicted) | [storage temp. ]
-86?C Freezer, Under Inert Atmosphere | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly) | [form ]
Oil | [pka]
-3.33±0.10(Predicted) | [color ]
Clear Pale Yellow to Yellow |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow Oil | [Uses]
2-Thiazolesulfonyl chloride is used for preparation of substituted thiazolesulfonamides as antiglaucoma agents.
| [Synthesis]
To a suspension of 2-mercaptothiazole (0.16 g, 1.37 mmol) in CH2Cl2 (14 mL) was added water (7 mL) followed by N-chlorosuccinimide (0.75 g, 5.6 mmol). The reaction mixture was stirred vigorously for 1.5 h. The reaction mixture was diluted with CH2Cl2, was |
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