| Identification | Back Directory | [Name]
Z433927330 | [CAS]
1005883-72-6 | [Synonyms]
Z433927330
Benzoic acid, 4-[[[[[4-(1H-pyrazol-1-yl)phenyl]methyl]amino]carbonyl]amino]-, ethyl ester | [Molecular Formula]
C20H20N4O3 | [MDL Number]
MFCD04280228 | [MOL File]
1005883-72-6.mol | [Molecular Weight]
364.4 |
| Chemical Properties | Back Directory | [Boiling point ]
532.4±50.0 °C(Predicted) | [density ]
1.23±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
13.00±0.46(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Z433927330 is a potent and selective inhibitor of Aquaporin-7 (AQP7), less potently inhibits AQP3 and AQPs9, with IC50s of ~0.2 μM, ~0.7 μM and ~1.1 μM for mAQP7, mAQP3 and mAQP9, respectively[1]. | [References]
[1] Z433927330, et al. Identification and characterization of potent and selective aquaporin-3 and aquaporin-7 inhibitors. J Biol Chem. 2019 May 3;294(18):7377-7387. DOI:10.1074/jbc.RA118.006083 |
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| Company Name: |
Twochem Co.Ltd.
|
| Tel: |
021-58111628 15800915896 |
| Website: |
cn.twochem.com |
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