| Identification | Back Directory | [Name]
9(R)-HODE | [CAS]
10075-11-3 | [Synonyms]
9(R)-HODE
9(R) HODE,9(R)HODE
NPDSHTNEKLQQIJ-WXUVIADPSA-N
9R-HYDROXY-10E,12Z-OCTADECADIENOIC ACID
10,12-Octadecadienoic acid, 9-hydroxy-, (9R,10E,12Z)- | [Molecular Formula]
C18H32O3 | [MDL Number]
MFCD00084832 | [MOL File]
10075-11-3.mol | [Molecular Weight]
296.44 |
| Chemical Properties | Back Directory | [Boiling point ]
416.1±33.0 °C(Predicted) | [density ]
0.970±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml | [pka]
4.78±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
9(R)-HODE is a monohydroxy fatty acid and metabolite of linoleic acid. It is formed from linoleic acid by COX and lipoxygenase (LO).9(R)-HODE induces chemotaxis, increases the levels of chemokine (C-C motif) receptor 9 (CCR9) and chemokine (C-X-C motif) receptor 4 (CXCR4), and inhibits IL-6 release in primary human monocytes. It inhibits CD3α- and CD28-induced proliferation of isolated human peripheral blood lymphocytes when used at a concentration of 25 μg/mL. | [Definition]
ChEBI: 9(R)-HODE is a 9-HODE in which the 9-hydroxy group has R-stereochemistry. It is a conjugate acid of a 9(R)-HODE(1-). It is an enantiomer of a 9(S)-HODE. | [References]
[1] Camacho, et al. Interleukin-1 enhances the ability of cultured human umbilical vein endothelial cells to oxidize linoleic acid. J. Biol. Chem. 270(29), 17279-17286 (1995). |
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Alfa Chemistry
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https://www.alfa-chemistry.com |
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Enzo Biochem Inc
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Enzo Biochem Inc. 13797054060 |
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www.enzo.com |
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