ChemicalBook--->CAS DataBase List--->100929-53-1

100929-53-1

Request For Quotation
100929-53-1 Structure

100929-53-1 Structure
IdentificationBack Directory
[Name]

DAGO ACETATE SALT
[CAS]

100929-53-1
[Synonyms]

DAMGO, DAGO
DAMGO acetate
DAGO ACETATE SALT
DAMGO ACETATE SALT
ala(2)-mephe(4)-gly(5)-enkephali
Enkephalin, Ala(2)-MePhe(4)-Gly(5)-
(D-ala2,N-me-phe4,gly5-ol)-enkephalin*acetate
TYR-D-ALA-GLY-N-METHYL-PHE-GLY-OL ACETATE SALT
DAGO, DAMGO, Tyr-D-Ala-Gly-N-methyl-Phe-Gly-ol
[D-ALA2,N-ME-PHE4,GLY5-OL]-ENKEPHALIN ACETATE SALT
(D-Ala?,N-Me-Phe?,glycinol?)-Enkephalin acetate salt
(D-alanine2,N-methylphenylalanine4,glycine3-ol)enkephalin
L-Tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-nalpha-methyl-L-phenylalaninamide monoacetate (salt)
L-Tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-N-alpha-methyl-L-phenylalaninamide monoacetate (salt)
L-Phenylalaninamide, L-tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-nalpha-methyl-, monoacetate (salt)
[Molecular Formula]

C28H39N5O8
[MDL Number]

MFCD00133215
[MOL File]

100929-53-1.mol
[Molecular Weight]

573.64
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[form ]

Powder
[InChIKey]

XZZYKCKUDLGXJA-NJUGUJQKSA-N
[SMILES]

CC(O)=O.C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C)[C@@H](Cc2ccccc2)C(=O)NCCO
[EPA Substance Registry System]

L-Tyrosyl-D-alanylglycyl-N-(2-hydroxyethyl)-N-.alpha.-methyl-L-phenylalaninamide monoacetate (salt) (100929-53-1)
Safety DataBack Directory
[WGK Germany ]

3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

[D-Ala2, N-Me-Phe4, Gly5-ol]-Enkephalin acetate salt or DAMGO has been used:
  • for use as a positive control in the assay of G-protein activation with μ-opioid receptor, to assay the inhibition of cAMP inhibition by DAMGO
  • for the determination of the suppression of contraction by opioid receptors
  • to determine whether the peripheral application of DAMGO suppresses the hypertonic saline (HS)-induced masseter nociception in slightly anaesthetized rats
[Uses]

Mu-opioid receptor-specific enkephalin analog
[General Description]

[D-Ala2, N-Me-Phe4, Gly5-ol]-Enkephalin acetate salt or DAMGO is a full agonist of the μ-opioid receptor. μ-opioid receptor is encoded by the OPRM1 gene, which has a predominant expression in reward-processing areas of brain. It acts as a receptor for endogenous opioids such as β-endorphin, encephalin, as well as foreign opioids such as morphine, heroin, and methadone.
[Biochem/physiol Actions]

Enkephalin analog that is a selective agonist at μ-opioid receptors.
100929-53-1 suppliers list
Company Name: CONIER CHEM AND PHARMA LIMITED
Tel: +8618523575427 , +8618523575427
Website: http://www.conier.com/
Company Name: Alfa Chemistry
Tel: +1-5166625404;
Website: https://www.alfa-chemistry.com/
Company Name: Chengdu Youngshe Chemical Co., Ltd.
Tel: +8618108235634 , +8618108235634
Website: http://www.youngshechem.com/
Company Name: Hangzhou MolCore BioPharmatech Co.,Ltd.
Tel: +86-057181025280; +8617767106207 , +8617767106207
Website: https://www.molcore.com/
Company Name: Nanjing TGpeptide
Tel: +86-13347807150
Website: tgpeptides.com/index.aspx
Company Name: Changsha MOL Changes Biotechnology Co., Ltd.
Tel: +8619375158599 , +8619375158599
Website: www.molchanges.com
Company Name: LEON (NANJING) BIOTECHNOLOGY CO., LTD.
Tel: +8615051830413 , +8615051830413
Website: www.njleonbiotech.com
Company Name: DONBOO AMINO ACID COMPANY
Tel: +8618051385538 , +8618051385538
Website: www.donboo.com/
Company Name: Shanghai Hanhong Scientific Co.,Ltd.  
Tel: 021-54306202 13764082696
Website: https://www.hanhongsci.com
Company Name: Chemsky（shanghai）International Co.,Ltd.  
Tel: 021-50135380
Website: www.shchemsky.com
Company Name: BOC Sciences  
Tel: 1-631-485-4226; 16314854226
Website: https://www.bocsci.com
Company Name: Sigma-Aldrich  
Tel: 021-61415566 800-8193336
Website: https://www.sigmaaldrich.cn
Company Name: Shanghai EFE Biological Technology Co., Ltd.  
Tel: 021-65675885 18964387627
Website: http://www.efebio.com
Company Name: Nanjing Leon Biological Technology Co., Ltd.  
Tel: 17705183659
Website: www.njleonbiotech.com
Company Name: Nanjing Peptide Biotech Ltd.  
Tel: 025-58361106-805 15951641583
Website: http://www.njpeptide.com
Company Name: Chengdu Youngshe Chemical Co., Ltd.  
Tel: +86-17380623303
Website: https://shop326109856.taobao.com/
Company Name: Hangzhou Peptidego Biotech Co.,Ltd.  
Tel: 0571-87213919
Website: http://peptidego.com
Company Name: Nanjing Meihao Pharmaceutical Technology Co., Ltd.  
Tel: meitaochem@126.com
Website: www.chemicalbook.com/ShowSupplierProductsList31244/0_EN.htm
Tags:100929-53-1 Related Product Information