| Identification | Back Directory | [Name]
GSK376501A | [CAS]
1010412-80-2 | [Synonyms]
GSK376501A
GSK376501A,GSK-376501A
1H-Indole-2-carboxylic acid, 1-[[3,5-bis(2-methoxyethoxy)phenyl]methyl]-3-[4-(1,1-dimethylethyl)phenyl]- | [Molecular Formula]
C32H37NO6 | [MDL Number]
MFCD30738670 | [MOL File]
1010412-80-2.mol | [Molecular Weight]
531.64 |
| Chemical Properties | Back Directory | [Boiling point ]
697.5±55.0 °C(Predicted) | [density ]
1.14±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
4.42±0.30(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
GSK376501A is a selective peroxisome proliferator-activated receptor gamma (PPARγ) modulator for the treatment of type 2 diabetes mellitus[1]. | [IC 50]
PPARγ | [References]
[1] Kae M. Bullock, et al. Process Development and Scale-Up of a PPARγ Agonist: Selection of the Manufacture Route. Org. Process Res. Dev. 2009, 13, 2, 303-309. |
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