| Identification | Back Directory | [Name]
2'-DEOXY-N6-METHYLADENOSINE 3',5'-BISPHOSPHATE TETRAAMMONIUM SALT | [CAS]
101204-49-3 | [Synonyms]
MRS2179 ammonium salt
MRS 2179, CID: 24867852
MRS2179tetraammoniumsalt
MRS 2179 TETRASODIUM SALT
MRS2179 hydrate ammonium salt
MRS 2179 ammonium salt hydrate
2'-DEOXY-N6-METHYLADENOSINE 3',5'-BISPHOSPHATE TETRASODIUM SALT
3'-Adenylic acid, 2'-deoxy-N-methyl-, 5'-(dihydrogen phosphate)
2'-DEOXY-N6-METHYLADENOSINE 3',5'-BISPHOSPHATE TETRAAMMONIUM SALT
[2-[(hydroxy-oxidophosphoryl)oxymethyl]-5-(6-methylaminopurin-9-yl)oxolan-3-yl] hydrogen phosphate | [Molecular Formula]
C11H17N5O9P2 | [MDL Number]
MFCD08544553 | [MOL File]
101204-49-3.mol | [Molecular Weight]
425.23 |
| Chemical Properties | Back Directory | [Boiling point ]
821.6±75.0 °C(Predicted) | [density ]
2.15±0.1 g/cm3(Predicted) | [storage temp. ]
−20°C | [solubility ]
DMSO: 1.1 mg/mL | [pka]
1.83±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
MRS 2179 ammonium salt hydrate has been used as a P2Y1 receptor antagonist in porcine coronary small arteries, endothelial cells, and hippocampal astrocytes. | [Biological Activity]
A competitive antagonist at P2Y 1 receptors (K B = 100 nM). Selective over P2X 1 (IC 50 = 1.15 μ M), P2X 3 (IC 50 = 12.9 μ M), P2X 2 , P2X 4 , P2Y 2 , P2Y 4 and P2Y 6 receptors. | [Biochem/physiol Actions]
MRS 2179 resists localized venous thrombosis and is useful in treating thrombotic syndromes due to its platelet aggregation inhibition functionality. |
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Sigma-Aldrich
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https://www.sigmaaldrich.cn |
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