| Identification | Back Directory | [Name]
2-Phenyl-3-methylquinoxaline | [CAS]
10130-23-1 | [Synonyms]
2-Methyl-3-phenylquinoxaline
2-Phenyl-3-methylquinoxaline
Quinoxaline,2-methyl-3-phenyl-
2-Methyl-3-phenylquinoxaline,97% | [Molecular Formula]
C15H12N2 | [MDL Number]
MFCD06653553 | [MOL File]
10130-23-1.mol | [Molecular Weight]
220.27 |
| Chemical Properties | Back Directory | [Melting point ]
57-58 °C | [Boiling point ]
165 °C(Press: 0.5 Torr) | [density ]
1.149±0.06 g/cm3(Predicted) | [solubility ]
DMF: 25 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:10): 0.1 mg/ml; Ethanol: 25 mg/ml | [form ]
A crystalline solid | [pka]
0?+-.0.48(Predicted) |
| Hazard Information | Back Directory | [Description]
2-phenyl-3-methyl-Quinoxaline is a synthetic intermediate useful for pharmaceutical synthesis. | [Uses]
2-Methyl-3-phenylquinoxaline (compound 38) is a potent platelet-derived growth factor receptor tyrosine kinase (PDGF-RTK) inhibitor with modest inhibitory activity against PDGFR kinase in intact cells (IC50 greater than 100 μM)[1]. | [References]
[1] Gazit A, et al. Tyrphostins. 5. Potent inhibitors of platelet-derived growth factor receptor tyrosine kinase: structure? activity relationships in quinoxalines, quinolines, and indole tyrphostins[J]. Journal of medicinal chemistry, 1996, 39(11): 2170-2177. DOI:10.1021/jm950727b |
|
| Company Name: |
Alfa Aesar
|
| Tel: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|