| Identification | Back Directory | [Name]
3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester | [CAS]
1014691-61-2 | [Synonyms]
CS-738
GSK 0660
GSK-0660, >=98%
GSK-0660 (GSK0660)
GSK0660 >=98% (HPLC)
GSK-0660;GSK 0660;GSK0660
4-Chloro-3-iodo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine
METHYL 3-[(4-ANILINO-2-METHOXYPHENYL)SULFAMOYL]THIOPHENE-2-CARBOXYLATE
Methyl 3-(N-(2-Methoxy-4-(phenylaMino)phenyl)sulfaMoyl)thiophene-2-carboxylate
3-(2-Methoxy-4-phenylamino-phenylsulfamoyl)-thiophene-2-carboxylic acid methyl ester
3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester
2-Thiophenecarboxylic acid, 3-[[[2-methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-, methyl ester | [Molecular Formula]
C19H18N2O5S2 | [MDL Number]
MFCD12828770 | [MOL File]
1014691-61-2.mol | [Molecular Weight]
418.49 |
| Chemical Properties | Back Directory | [Boiling point ]
608.1±65.0 °C(Predicted) | [density ]
1.413±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: soluble10mg/mL, clear | [form ]
powder | [pka]
8.51±0.50(Predicted) | [color ]
white to beige | [InChIKey]
NDFKBGWLUHKMFY-UHFFFAOYSA-N |
| Hazard Information | Back Directory | [Uses]
GSK0660 has been used to study the effects of bezafibrate (BZA) on hypertrophy. | [Definition]
ChEBI: 3-[(4-anilino-2-methoxyphenyl)sulfamoyl]-2-thiophenecarboxylic acid methyl ester is a sulfonamide. | [General Description]
GSK0660 has antiangiogenic property in oxygen-induced retinopathy. It also regulates tumor necrosis factor-α (TNFα)-induced inflammation in human retinal microvascular endothelial cells (HRMECs). | [Biochem/physiol Actions]
GSK0660 is a potent PPARβ/δ antagonist with a pIC50 of 6.8 (160 nM). GSK0660 is nearly inactive on PPARα and PPARγ with IC50s greater than 10 μM. | [storage]
Store at -20°C |
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