| Identification | Back Directory | [Name]
-N7-DGTP | [CAS]
101515-08-6 | [Synonyms]
-N7-DGTP
7-DEAZA-DGTP, LI
-N7-dGTP, 7-Deaza-dGTP
7-DEAZA-DGTP LITHIUM SALT
7-Deaza-2'-dGTP lithium salt
7-Deaza-dGTP，Sodium solution
2'-deoxy-7-deazaguanosine triphosphate
7-deaza-2'-deoxyguanosine 5'-*triphosphate lithiu
7-DEAZA-2'-DEOXYGUANOSINE 5'-*TRIPHOSPHA TE LITHIUM
7-DEAZA-2'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE LITHIUM SALT
7-DEAZA-2'-DEOXYGUANOSINE-5'-TRIPHOSPHORIC ACID, LITHIUM
7-Deaza-2'-deoxyguanosine 5'-triphosphate lithium salt 10 mM in H2O
7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt - 10mM aqueous solution
7-Deaza-2'-deoxyguanosine-5′-triphosphate lithium salt - 100mM aqueous solution
4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-7-[2-deoxy-5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-erythro-pentofuranosyl]-3,7-dihydro- | [Molecular Formula]
C11H17N4O13P3 | [MDL Number]
MFCD00171614 | [MOL File]
101515-08-6.mol | [Molecular Weight]
506.19 |
| Chemical Properties | Back Directory | [density ]
2.48±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [form ]
solution | [pka]
0.97±0.50(Predicted) | [color ]
colorless | [biological source]
Porcine muscle
rabbit muscle | [InChIKey]
CEGUJIMDPFZZHS-JEBNKXSCNA-M | [SMILES]
C12NC(=NC(=O)C=1C=CN2[C@H]1C[C@H](O)[C@@H](COP(=O)(O)OP(=O)(O)OP([O-])(=O)O)O1)N.[Li+] |&1:10,12,14,r| |
| Hazard Information | Back Directory | [Uses]
7-Deaza-dGTP is a substrate for most DNA polymerases, including Taq DNA polymerase.
7-Deaza-dGTP is used in the dideoxy-chain termination sequencing methods, in place of dGTP to overcome compression problems in gel electrophoresis when sequencing GC-rich stretches of DNA.
Partial substitution of 7-Deaza-dGTP for dGTP in PCRs can improve the product yield when the template is GC-rich (i.e., has extensive secondary structures). | [General Description]
7-Deaza-2′-deoxyguanosine 5′-triphosphate enhances polymerase chain reaction (PCR) product yield. | [Biochem/physiol Actions]
This dGTP analog pairs weakly with conventional bases to minimize DNA secondary structures, while being a good substrate for DNA ploymerases. |
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BOC Sciences Gold
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Sigma-Aldrich
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Energy Chemical
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