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101762-87-2

101762-87-2 Structure

101762-87-2 Structure
IdentificationBack Directory
[Name]

N-Benzyloctadecenamide
[CAS]

101762-87-2
[Synonyms]

N-Benzyloctadecenamide
(9Z)-N-(Phenylmethyl)-9-octadecenamide
9-Octadecenamide, N-(phenylmethyl)-, (9Z)-
[Molecular Formula]

C25H41NO
[MOL File]

101762-87-2.mol
[Molecular Weight]

371.6
Chemical PropertiesBack Directory
[Melting point ]

58-59 °C
[Boiling point ]

534.2±39.0 °C(Predicted)
[density ]

0.923±0.06 g/cm3(Predicted)
[pka]

16.39±0.46(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319
[Precautionary statements ]

P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Hazard InformationBack Directory
[Description]

N-Benzyloleamide is a natural compound found in a variety of plants such as Tropaeolum tuberosum tubers and Lepidium meyenii (Maca). N-Benzyloleamide has been shown to have anti-inflammatory activity with IC50 values of 6.50±0.75 μM, 7.74±0.19 μM, and 8.37±0.09 μM in CCD-1109Sk, MRC-5, and RWPE-1 cell lines, respectively[1].  In addition, it has been shown to have a concentration-dependent inhibitory effect on fatty acid amide hydrolase (FAAH), an enzyme responsible for the degradation of endogenous cannabinoids in the nervous system[2].
[Uses]

N-Benzyloctadecenamide is a natural product[1].
[References]

[1] TICONA L A, COBALLES M R, POTENTE G, et al. Anti-inflammatory Potential of Macamides Isolated from Yellow Tubers of Mashua (Tropaeolum Tuberosum)[J]. Planta Medica International Open, 2020. DOI:10.1055/a-1159-4242.
[2] M ALASMARI. Inhibition of Fatty Acid Amide Hydrolase (FAAH) by Macamides.[J]. Molecular Neurobiology, 2019. DOI:10.1007/s12035-018-1115-8.
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