| Identification | Back Directory | [Name]
N1,N1-Diethyl-N6-(6-methoxy-4-methyl-8-quinolinyl)-1,6-hexanediamine 4-methylbenzenesulfonate | [CAS]
1019640-33-5 | [Synonyms]
Sitamaquine tosylate
Sitamaquine - WR 6026 tosylate
Sitamaquine tosylate >=98% (HPLC)
N,N-diethyl-N'-[4-methyl-6-(methyloxy)-8-quinolinyl]-1,6-hexanediamine tosylate
N1,N1-Diethyl-N6-(6-methoxy-4-methyl-8-quinolinyl)-1,6-hexanediamine 4-methylbenzenesulfonate | [Molecular Formula]
C28H41N3O4S | [MDL Number]
MFCD17392572 | [MOL File]
1019640-33-5.mol | [Molecular Weight]
515.708 |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C | [solubility ]
DMSO: 30 mg/ml | [form ]
powder | [color ]
white to beige | [Water Solubility ]
H2O: 15mg/mL, clear | [InChIKey]
LOBPWLFCZDGYKW-UHFFFAOYSA-N | [SMILES]
C(N(CC)CC)CCCCCNC1C2C(C=C(OC)C=1)=C(C)C=CN=2.C1(S(O)(=O)=O)=CC=C(C)C=C1 |
| Hazard Information | Back Directory | [Uses]
Sitamaquine is an orally active 8-aminoquinoline analog that exhibit antiplasmodial and antileishmanial activities. | [Biological Activity]
Sitamaquine is also known as WR-6026. It is used in the treatment of visceral leishmaniasis.', 'Sitamaquine is an orally active 8-aminoquinoline analog th at exhibit antiplasmodial and antileishmanial activities. Sitamaquine accumulates in Leishmania parasites. Sitamaquine potently inhibits respiratory chain complex II (succinate dehydrogenase), which leads to an apoptosis-like death of Leishmania parasites. | [IC 50]
Leishmania |
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